Shift + F10 right-clicks.
Win + L (XP Only): Locks keyboard. Similar to Lock Workstation.
Win + F or F3: Open Find dialog. (All Files) F3 may not work in some applications which use F3 for their own find dialogs.
Win + Control + F: Open Find dialog. (Computers)
Win + U: Open Utility Manager.
Win + F1: Open Windows help.
Win + Pause: Open System Properties dialog.
Win + Tab: Cycle through taskbar buttons. Enter clicks, AppsKey or Shift + F10 right-clicks.
Win + Shift + Tab: Cycle through taskbar buttons in reverse.
Alt + Tab: Display Cool Switch. More commonly known as the AltTab dialog.
Alt + Shift + Tab: Display Cool Switch; go in reverse.
Alt + Escape: Send active window to the bottom of the z-order.
Alt + Shift + Escape: Activate the window at the bottom of the z-order.
Alt + F4: Close active window; or, if all windows are closed, open shutdown dialog.
Shift while a CD is loading: Bypass AutoPlay.
Shift while login: Bypass startup folder. Only those applications will be ignored which are in the startup folder, not those started from the registry (Microsoft\Windows\CurrentVersion\Run\)
Ctrl + Alt + Delete or Ctrl + Alt + NumpadDel (Both NumLock states): Invoke the Task Manager or NT Security dialog.
Ctrl + Shift + Escape (2000/XP ) or (Ctrl + Alt + NumpadDot) : Invoke the task manager. On earlier OSes, acts like Ctrl + Escape.
Print screen: Copy screenshot of current screen to clipboard.
Alt + Print screen: Copy screenshot of current active window to clipboard.
Ctrl + Alt + Down Arrow: Invert screen. Untested on OS's other than XP.
Ctrl + Alt + Up Arrow: Undo inversion.
Win + B : Move focus to systray icons.
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Ctrl + C or Ctrl + Insert: Copy.
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Ctrl + X or Shift + Delete: Cut.
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Ctrl + V or Shift + Insert: Paste/Move.
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Ctrl + N: New... File, Tab, Entry, etc.
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Ctrl + S: Save.
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Ctrl + O: Open...
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Ctrl + P: Print.
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Ctrl + Z: Undo.
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Ctrl + A: Select all.
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Ctrl + F: Find...
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Ctrl+W : to close the current window
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Ctrl + F4: Close tab or child window.
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F1: Open help.
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F11: Toggle full screen mode.
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Alt or F10: Activate menu bar.
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Alt + Space: Display system menu. Same as clicking the icon on the titlebar.
- Escape: Remove focus from current control/menu, or close dialog box.
General Navigation
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Tab: Forward one item.
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Shift + Tab: Backward one item.
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Ctrl + Tab: Cycle through tabs/child windows.
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Ctrl + Shift + Tab: Cycle backwards through tabs/child windows.
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Enter: If a button's selected, click it, otherwise, click default button.
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Space: Toggle items such as radio buttons or checkboxes.
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Alt + (Letter): Activate item corresponding to (Letter). (Letter) is the underlined letter on the item's name.
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Ctrl + Left: Move cursor to the beginning of previous word.
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Ctrl + Right: Move cursor to the beginning of next word.
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Ctrl + Up: Move cursor to beginning of previous paragraph. This and all subsequent Up/Down hotkeys in this section have only been known to work in Rich Edit controls.
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Ctrl + Down: Move cursor to beginning of next paragraph.
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Shift + Left: Highlight one character to the left.
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Shift + Right: Highlight one character to the right.
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Shift + Up: Highlight from current cursor position, to one line up.
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Shift + Down: Highlight from current cursor position, to one line down.
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Ctrl + Shift + Left: Highlight to beginning of previous word.
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Ctrl + Shift + Right: Highlight to beginning of next word.
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Ctrl + Shift + Up: Highlight to beginning of previous paragraph.
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Ctrl + Shift + Down: Highlight to beginning of next paragraph.
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Home: Move cursor to top of a scrollable control.
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End: Move cursor to bottom of a scrollable control.